Blog
Slide tutorial – Case 7
Clinical history: 65yo male, TURBT
Digital slide: H&E (x40) – Review before progressing
Macroscopic and microscopic images:
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- Low power papillary outline
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- papillae composed of fibrovascular cores lined by thickened urothelium
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- Thickened urothelial layer with high grade cytological atypia, suprabasal mitotic and apoptotic activity and early architectural disorder
Diagnosis:
Video tutorial
Case discussion
This is presented;
- as a common neoplastic condition of the urinary tract
- to raise the classification and grading of urothelial lesions
The key features to take away include;
- The architectural and cytological features of high grade dysplasia
- Key features in reporting of urothelial lesions
Extended learning topics
Discuss key elements to report in TURBT specimens
Discuss the ISUP/WHO classification of urothelial lesions
Drop me a line or call me at TissuPath if you want to discuss any of these cases further
Andrew
This case has been de-identified and is intended for educational purposes only
