Case study – Papillary variant acinic cell carcinoma


Papillary variant acinic cell carcinoma is an uncommon salivary gland lesion, most commonly seen in the parotid gland

Here is an example – Click here to review as digital slide


Medium power, lesion on left - papillary architecture, fibrous capsule

High power - Papillary architecture, uniform cells with abundant cytoplasm

Case discussion:

This is an uncommon variant of an uncommon tumour and is presented here as an rarity

Morphological features include;

  • Circumscription
  • Low power papillary architecture
  • Uniform oncocytic cells
  • Large prominent nucleoli

Prognostic features include;

  • Small
  • Confined to gland
  • Clear of margins


  • Surgical

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